Medi-Weightloss Franchise: Costs, Fees, & Profit Data for 2025

Franchise Opportunity Deep Dive: Medi-Weightloss is a leading brand in physician-supervised weight loss, offering science-backed, physician-led services to combat the obesity epidemic.

REPORTED COST TO GET IN: $251,000 - $494,000

REPORTED ROI (Item 19): $794,551 (average gross revenue, FY 2024)

Medi-Weightloss is a nationally recognized franchise specializing in non-surgical, physician-supervised weight management. Known for its evidence-based programs and clinical oversight, the brand offers a trusted solution for individuals seeking long-term weight loss support. Backed by private equity firm Audax Group and based in Tampa, Florida, the brand has helped clients lose over 9.2 million pounds.

The company was founded in 2005 in Tampa, Florida, by Edward Kaloust, in collaboration with a team of physicians and health care professionals. It began franchising shortly after its founding and has since grown into a leading name in medical weight loss. In 2025, Brian Petranick — former group president at Neighborly and CEO of Right at Home* — was appointed CEO to guide the brand’s next phase of growth.

Mission: To fight the obesity epidemic in America through science-backed, physician-supervised weight loss programs.

• Medically supervised and clinically proven programs

• Proprietary supplements and nutritional products

• Vitamin and nutrient injections, IV therapy, and prescription solutions

• Individualized care plans and long-term maintenance programs

• Pediatric weight loss services for ages 12-18

• Proven business model and national brand recognition

• Protected territories and turnkey clinic model

• Comprehensive training, marketing, and compliance support

• Revenue streams from consultations, products, and in-office therapies

• Flexibility to operate as a medical professional or management entity

Initial Costs: The estimated initial investment required to begin operation of a Medi-Weightloss franchise ranges from $251,000 to $494,000. The 2025 Franchise Disclosure Document (FDD) breaks these costs down as follows:

Initial Franchise Fee: The franchise fee is $60,000, which is payable upon signing the franchise agreement. Area developers pay reduced per-unit fees based on the number of franchises.

Ongoing Fees: According to the 2025 FDD, Medi-Weightloss franchisees are responsible for the following ongoing payments and fees:

ROI Potential: According to the 2025 FDD, the 57 businesses operating for the entirety of FY 2024 reported the following gross profit:

Training Programs

• In-person training at headquarters in Tampa, Florida

• Ongoing on-site training and eLearning

• Educational resources and compliance audits

Operational Support

• Grand opening campaign execution

• On-call operations and clinic management support

• Regional and national advertising support

Technology and Tools

• Practice management software

• EMR and prescription labeling systems

• Online ordering platform and HIPAA-compliant systems

Eligibility Criteria

• Health care professionals can operate directly (Health Care Business)

• Non-licensed investors can manage the business (Management Business) with licensed medical providers handling patient care

Operational Commitments

• Full-time management recommended

• Clinic must comply with all medical regulations and HIPAA laws

Funding Assistance

• No in-house financing offered

• Franchisees are encouraged to consult legal and financial professionals

“The revenue generation has exceeded our expectations without question. It’s a challenge in figuring out, as any business model grows, how do you grow at a proper pace, to change your operations and to be able to handle the load.”

• Kurtis Freidag, Multi-Unit Owner, Illinois

The U.S. weight loss industry is valued at $3.5 billion, with a larger global market projected to reach $295.3 billion by 2027. Over 73% of U.S. adults are overweight or obese, creating a significant and sustained demand for effective, personalized weight loss programs.

Competitor Analysis

Medi-Weightloss sets itself apart with a physician-supervised, science-based approach to weight management, offering a turn-key franchise model with exclusive territories, proprietary EMR software and multiple revenue streams through programs like diabetes care and corporate wellness. Backed by strong operational support and clinical credibility, the brand delivers both proven outcomes and a scalable business model.

The brand’s primary competitors include BeBalanced Natural Hormone Weight Loss, Inspire Weight Loss, LeanMD and Lindora.

1. Introductory Call and Business Overview Presentation: Kick things off with an initial call to learn about the brand, its model and how the opportunity aligns with your goals.

2. Documents Review: Review the FDD, complete an NDA and submit your franchise application to begin due diligence.

3. Leadership Meetings: Meet with team members from Operations, Medical Affairs and Marketing to dive deeper into the support and structure of the system.

4. Deeper-Dive Call: Reconnect with the franchise team to address remaining questions, explore available territories and assess next steps.

5. Validation Calls With Current Franchisees: Speak with existing owners to gain real-world insights into the franchise experience and performance.

6. Day of Discovery: Visit Medi‑Weightloss headquarters in Tampa to meet leadership, tour the facility and experience the brand firsthand.

7. Agreement Review: Receive and review your personalized franchise agreement, outlining all commitments and expectations before signing.

8. Welcome to the Team: Once the agreement is signed, you officially begin onboarding, training and preparation to open your Medi‑Weightloss clinic.

Complete the online inquiry form to get started.

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